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Cleanroom Utility Systems

Sterilize-in-Place System

A monitored clean-steam distribution skid that sequences steam admission, air removal, hold time and condensate discharge across connected hygienic process circuits.
  • Sequenced clean-steam admission
  • Drainable condensate management
  • Multi-point temperature monitoring
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Product Introduction

The Sterilize-in-Place System receives qualified clean steam, separates entrained condensate and routes steam through an automated hygienic valve manifold to connected vessels, piping or filling circuits. Pressure, drain and temperature instruments support controlled air displacement, exposure and cooling phases without dismantling the process path.

Key Features

Polished 316L clean-steam contact path

Vertical inlet separator

Automated multi-branch valve manifold

Low-point thermostatic condensate removal

Independent branch temperature inputs

Pressure indication and regulation interface

Recipe-based sterilization sequencing

HMI alarms and phase status

Customer Product Concerns

Effective SIP depends on removing air and condensate, exposing every wetted surface to the selected condition and documenting stable hold points without damaging seals or instruments.

Cold pockets form behind retained condensateProvide sloped branches and dedicated hygienic traps at verified low points before starting the exposure hold.
Parallel circuits heat at different ratesSequence branch valves and monitor representative return temperatures independently.
Steam pressure varies during valve changesCoordinate inlet pressure control with staged branch admission and live pressure indication.
Operators cannot distinguish exposure from coolingUse recipe phases, permissives and alarms to separate air purge, heat-up, hold, depressurization and cooling.

Typical Applications

Bioreactor and fermenter circuitsSterile transfer pipingAseptic filling product pathsPharmaceutical process vesselsHygienic filtration housings

Technical Parameters

Branch count, steam demand, valve sizing, trap capacity, temperature inputs and sequencing logic are selected for the connected equipment and approved sterilization cycle.

Core Material316L stainless steel clean-steam separator, header and hygienic branch piping
Panel ThicknessSeparator shell typically 2.0–5.0 mm
Effective WidthSkid width typically 900–2200 mm
Maximum LengthComplete skid length typically up to 3500 mm
Steel Facing ThicknessControl enclosure and skid sheet typically 1.5–3.0 mm
Core Density316L stainless steel density approximately 8000 kg/m³
Thermal Conductivity316L stainless steel approximately 15 W/(m·K) at ambient temperature
Surface FinishPolished clean-steam surfaces with satin-finished skid and control enclosure
Joint TypeOrbital-welded hygienic header with sanitary clamps at valves, instruments and condensate trap
CustomizationAvailable based on the intended application and operating environment.

Available Options

Two to eight sterilization branchesSteam pressure-reducing stationBranch return-temperature sensorsHygienic thermostatic steam trapsSterile-air cooling interfaceRecipe and batch-report communicationInsulated steam piping

Planning a Sterilize-in-Place System specification?

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