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Laminar Flow and Containment Equipment

Cytotoxic Containment Isolator

A negative-pressure glovebox that contains cytotoxic and other hazardous drug preparation through sealed manipulation, transfer and waste paths.
  • Negative-Pressure Hazardous Drug Chamber
  • Closed Glove Manipulation
  • Staged Exhaust Filtration
  • Contained Waste Egress
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Product Introduction

The cytotoxic isolator encloses hazardous drug manipulation inside a negative-pressure stainless chamber. Glove ports provide operator access, while an interlocked transfer chamber introduces materials without opening the main work zone. Exhaust air passes through staged high-efficiency filtration, and sharps, liquid and solid waste can leave through dedicated closed connections. The pressure and airflow arrangement prioritize personnel and environmental containment while maintaining a clean work zone for the product.

Key Features

Negative pressure keeps leakage direction inward toward the filtered exhaust.

Glove manipulation separates the operator from hazardous drug aerosols and residues.

Staged exhaust filters provide redundant particulate retention.

A sealed transfer chamber limits direct room-to-work-zone openings.

Dedicated sharps and bag-out interfaces keep waste within closed routes.

Customer Product Concerns

Hazardous drug work requires the work chamber, transfer route and waste system to maintain containment through the complete compounding cycle.

Waste containers leave the chamber through the clean supply route.Separate sharps, liquid and bag-out ports create dedicated egress paths.
A glove puncture weakens the primary barrier.Replaceable glove rings and integrity-test connections support routine barrier management.
Filter service exposes concentrated hazardous residue.Contained filter-change housings isolate loaded exhaust stages.
Pressure becomes positive during exhaust failure.Pressure monitoring and exhaust interlocks alarm or stop operation when containment is lost.

Typical Applications

Cytotoxic drug compoundingAntineoplastic preparationHazardous sterile admixturesOncology pharmacy manipulation

Technical Parameters

Typical configurable construction ranges for a cytotoxic containment isolator are listed below.

Core MaterialWelded SUS316L negative-pressure chamber with laminated glass, CSM gloves and staged safe-change exhaust filters
Panel Thickness50-100 mm double-skin chamber and exhaust sections
Effective Width1200-3000 mm usable compounding width
Maximum LengthUp to 4500 mm overall isolator length
Steel Facing Thickness2.0-3.0 mm SUS316L chamber; 1.2-1.5 mm service skins
Core DensityApproximately 8000 kg/m³ for SUS316L chamber material
Thermal Conductivity14-16 W/(m·K) for austenitic stainless steel
Surface FinishElectropolished SUS316L interior with welded spill-retaining lower pan
Joint TypePressure-tight welded chamber with sealed glove rings, gasketed transfer hatch and contained exhaust-filter collars
CustomizationAvailable based on the intended application and operating environment.

Available Options

Two to four glove positionsSharps and liquid waste portsBag-out solid-waste systemIntegrated glove integrity tester

Planning a Cytotoxic Containment Isolator specification?

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