Laminar Flow and Containment Equipment

Cytotoxic Drug Safety Cabinet

A negative-pressure safety cabinet configured with enhanced filtration and dedicated exhaust for contained preparation of cytotoxic and other hazardous drug products.

Hazardous Drug Containment
Inward Operator Protection
Filtered Product Downflow
Enhanced Exhaust Filtration

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Product Introduction

The cytotoxic cabinet uses an open-front Class II-style airflow pattern with inward capture and filtered vertical downflow, combined with dedicated exhaust and enhanced filter staging for hazardous drug work. A leak-tight stainless work zone, removable segmented tray and negative-pressure plenums reduce contamination traps. The exhaust method, filter arrangement and room installation are selected for the facility's hazardous drug handling program rather than described as one universal cabinet type.

Key Features

Inward face airflow opposes hazardous aerosol movement toward the operator.

Filtered downflow protects prepared products and limits work-zone cross-contamination.

Additional exhaust filtration provides a secondary particulate barrier.

Negative-pressure plenums surround contaminated air paths.

A segmented work tray and spill pan support controlled cleaning after compounding.

Customer Product Concerns

Hazardous drug preparation must protect the operator, product and surrounding environment while supporting controlled cleanup of spills and residues.

Aerosols can escape through the front opening during manipulation.Stable inward airflow and a defined sash height maintain the operator boundary.

Residue accumulates beneath the work surface.Segmented lift-out trays expose a stainless spill pan for cleaning.

A single filter stage offers limited redundancy.Enhanced supply and exhaust filter staging adds particulate barriers in the airflow path.

Exhaust configuration is selected without room coordination.The cabinet connection is matched to the facility exhaust and hazardous drug procedure.

Typical Applications

Cytotoxic drug preparationAntineoplastic compoundingHazardous sterile admixture setupOncology pharmacy support

Technical Parameters

Typical configurable construction ranges for a cytotoxic drug safety cabinet are listed below.

Core Material	SUS316L work-zone liner with powder-coated steel outer shell and mineral-wool insulated negative-pressure plenums
Panel Thickness	40-75 mm double-skin cabinet and exhaust sections
Effective Width	900-1800 mm clear working width
Maximum Length	Up to 2600 mm overall cabinet height
Steel Facing Thickness	1.2-1.5 mm SUS316L work-zone liner; 1.0-1.2 mm outer steel
Core Density	100-140 kg/m³ mineral-wool plenum insulation
Thermal Conductivity	0.035-0.045 W/(m·K) for the mineral-wool insulation
Surface Finish	Fine-brushed or electropolished SUS316L with sealed white outer coating
Joint Type	Welded negative-pressure work zone with gasketed staged-filter housings and flanged exhaust connection
Customization	Available based on the intended application and operating environment.

Available Options

Total exhaust or evaluated recirculating arrangementMotorized sashAdditional exhaust HEPA stageClosed-transfer compounding accessories

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