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Industry-Specific Cleanroom Equipment
High-Potency Containment Isolator
A negative-pressure stainless-steel isolator that separates operators from potent compounds during weighing, charging, sampling and other powder-handling operations.
- Negative-Pressure Barrier
- Double Exhaust Filtration
- Integrated Transfer Chamber
- Glove-Based Process Access
Product Introduction
The high-potency containment isolator combines a welded stainless enclosure, sealed viewing panels and glove access with controlled inward airflow. A staged transfer chamber supports material entry and removal without opening the principal process zone directly to the room. Dedicated inlet and exhaust filtration, pressure monitoring and a cleanable lower utility section support repeatable potent-compound handling while keeping process equipment visible and accessible.
Key Features
Two-stage exhaust filtration provides a redundant barrier for airborne powder.
Four glove ports give operators reach across the three-panel working chamber.
A gasketed side transfer chamber separates material movement from the primary workspace.
Customer Product Concerns
Highly potent powders can migrate through open handling steps, expose personnel and make product changeover difficult to control.
Open scooping or charging can disperse potent dust into the room.A sealed negative-pressure chamber keeps manipulation behind glass and glove barriers.
Removing tools or containers can breach the primary workspace.The interlocked side chamber stages transfers before either boundary door is opened.
A single exhaust element offers limited protection during filter loading.Series exhaust stages and monitored airflow provide a more robust airborne-powder barrier.
Residue trapped around fittings lengthens campaign changeover.Smooth stainless surfaces, rounded internal transitions and accessible service connections support wash-down and inspection.
Typical Applications
HPAPI dispensing and weighingPotent powder samplingContained reactor or granulator chargingOncology solid-dose development
Technical Parameters
Typical configurable construction values for a multi-glove high-potency containment isolator are listed below.
| Core Material | Welded 316L stainless-steel chamber with laminated safety glass and black butyl gloves |
|---|---|
| Panel Thickness | 50-100 mm insulated enclosure sections |
| Effective Width | 1800-2600 mm usable chamber width |
| Maximum Length | Up to 3200 mm overall equipment length |
| Steel Facing Thickness | 2-3 mm chamber wall and work-surface construction |
| Core Density | 7950-8050 kg/m³ for stainless-steel construction |
| Thermal Conductivity | 14-16 W/(m·K) for austenitic stainless steel |
| Surface Finish | Satin exterior with smooth mechanically polished product-contact interior |
| Joint Type | Fully welded chamber with gasketed viewing panels, glove rings and interlocked transfer doors |
| Customization | Available based on the intended application and operating environment. |
Available Options
Integrated wash-in-place spray systemBag-in/bag-out exhaust filter housingsRapid transfer or split butterfly valve interfacesApplication-specific process equipment integration
Planning a High-Potency Containment Isolator specification?
Send us your dimensions, installation conditions, performance targets and required surface finish.
